Symptomatic infection will usually respond to polyene agents (nystatin) or to one of a variety of imidazole antifungal agents (e.g. clotrimazole, econazole, isoconazole or miconazole) used in accordance with the manufacturer’s instructions. Typical regimens include:
Nystatin vaginal pessaries or tablets (100,000 U) 1 or 2 pessaries or tablets daily for 2 weeks or topical imidazole (various preparations) inserted high in the vagina at bedtime (once daily) for 6 days or in higher doses for 3 days.
Imidazole preparations should not be used in pregnancy.
Vaginal creams may be used for treatment of vulval candidiasis.
clotrimazole one 500 mg vaginal tablet) can be used.
Supportive measures include good personal hygiene and loose fitting cotton underwear. Use of paper after micturition or defaecation should be in an antero posterior direction to reduce the risk of reinfection. If candidiasis is associated with use of an oral contraceptive, a reduced dose of progesterone can be tried or other methods substituted.
problem. Antifungal therapy should be considered for the male partner if he is uncircumcised. Combined oral and topical antifungal therapy for the patient and partner maybe effective in difficult cases by eradicating reservoirs of infection in the genital and gastrointestinal tracts.

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